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Cusson (Apiaceae), Tetradium ruticarpum (A.Juss) T.G.Hartley (Rutaceae) and Kaempferia galanga L (Zingiberaceae), was found to increase the activities of enzymatic antioxidants, such as CuZn-superoxide dismutase (SOD), and levels of non-enzymatic antioxidants, such as GSH and alpha-tocopherol (a-TOC) in rat brain, heart, liver and skeletal muscle tissues in vivo ( Yang/Qi-Invigorating Tonic Botanical Drugs/Herbal Formulations Ameliorate Chronic Kidney Disease In laboratories, many single Yang/Qi-invigorating botanical drugs have been shown to provide renal protective effects in animals